Bolivia & Peru

Altitude, Andes & Ancient Trails

Duration
20-28 days (extendable)
Trip style
Nature/ Hiking
Effort
Challenging
Region
Americas

Three weeks across Bolivia and Peru: tracing a high-altitude route through the Andes from the surreal Salar de Uyuni to the sacred peaks of Machu Picchu

From the dizzying streets of La Paz to the white peaks of the Andes, this journey follows South America’s spine, salt deserts, ancient trails, sacred lakes and cities carved into cloud and stone

This route crosses the heart of the Andes, combining Bolivia’s wild landscapes with Peru’s ancient history.

Start in La Paz, one of the world’s highest capitals, where cable cars glide above a basin of red cliffs. From there, head south to the Salar de Uyuni, a vast salt desert stretching into infinity. Return north for the world’s highest navigable lake, Titicaca, before crossing into Peru to explore Arequipa’s colonial streets, Colca Canyon’s condors, and Cusco, the heart of the Inca Empire.

End the trip with the Salkantay Trek to Machu Picchu, then unwind on the coast with desert dunes and vineyards in Huacachina.

Highlights

Salar de Uyuni: Salt, Silence & Stars

Salar de Uyuni: Salt, Silence & Stars

A white desert that bends perspective, endless horizon, mirror reflections, flamingos and fossil islands, where salt is the constant everywhere you look (including the walls of your accommodation!). A 3 day expedition here is the perfect amount of time to take it all in.

Salkantay trek to Macchu Picchu

Salkantay trek to Macchu Picchu

A 4-day trek reaching 4,650m traversing across snow peaks and cloud forest, with view of glaciers and emerald lakes, to reach Machu Picchu, the jewel of Incan engineering.

Isla del Sol on Lake Titicaca

Isla del Sol on Lake Titicaca

Isla del Sol is a sacred site in Inca mythology believed to be the birthplace of the sun and first Incas, offering stunning views, ancient ruins, and traditional Aymara/ Quechua villages with rustic charm, no cars, and great hiking.

The route

Day 1: Arrive in La Paz

Day 2: Explore La Paz

Day 3: La Paz to the Salar de Uyuni

Day 4: Across the Uyuni salt flats and altiplano

Day 5: Uyuni return and overnight bus to La Paz

Day 6: La Paz recovery day

Day 7: Death Road from La Paz

Day 8: La Paz to Copacabana and Isla del Sol

Day 9: Isla del Sol to Arequipa

Day 10: Explore Arequipa

Day 11: Colca Canyon day trip

Day 12: Arequipa to Cusco

Day 13: Begin the Salkantay Trek

Day 14: Salkantay Trek

Day 15: Salkantay Trek

Day 16: Machu Picchu and return to Cusco

Day 17: Cusco to Huacachina via Lima

Day 18: Huacachina oasis and dunes

Day 19: Lima coastal finale

Day 20: Fly out

Start the journey

The first part of the day-by-day route, free to read.

Days 1–2: La Paz, Life at 3,600 Metres

Arrive in La Paz, Bolivia’s chaotic, breathtaking capital. The altitude hits fast so walk slowly and drink local teas.

Join a free walking tour through the Witches’ Market and colonial streets, and take the Mi Teleférico cable cars for panoramic rides over the bowl-shaped city. Each line offers a different view of the sprawling Andean metropolis and is a great way to see the city from above.

Spend an evening at Mirador Killi Killi or the rooftop bar of Selina La Paz. Prepare for the long overnight bus to Uyuni.

Get the full Bolivia & Peru itinerary

  • The rest of the day-by-day route, 7 more detailed entries
  • Where to stay, by budget
  • Where to eat and drink
  • Practical reminders and cautions
  • Ways to shorten or extend the trip
  • 25 photos from the trip
  • A direct line to the traveller who led it

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From travellers on this trip

“The Salkantay Trek was one of the hardest but most rewarding things I’ve ever done. You earn every step of that Machu Picchu sunrise. Machu Picchu Reservations organises this trek methodologically, with all accommodation and food organised, and the vibes of the people in the group amazing, especially the pre-dawn hike Karaoke in Aguas Calientes!”

Max Vienna, Austria

“The Salar de Uyuni in Bolivia were unexplainable - the optical illusions associated with kilometres of salt water reflecting the sun created some colours I'd never seen before, and the rocky "islands" scattered across the landscape created amazing contrasts. 3 days here was the perfect length to truly appreciate the beauty of this place”

Edoardo Milan, Italy

“An exhausting but unforgettablee trip: the landscapes don’t make sense: one day it’s a desert of mirrors, the next you’re watching condors at sunrise. An always at crazy elevations! You feel like your at the roof of the world in a mystical setting powered by ancient mythologies and legends.”

Clara Madrid, Spain